1 - 6 August 1999
Kona Surf Resort and Conference
Center
78-128 Ehukai Street
Kailua-Kona, Hawaii 96740
Phone: 1-808-322-3411
Conference Co-Chairs:
Dr. David Benaron
Stanford University
Dr. Eva M. Sevick-Muraca
Purdue University
Dr. Arjun G. Yodh
University of Pennsylvania
United Engineering Foundation,
Inc.
Three Park Avenue, 27th
Floor
New York, NY 10016-5902
T: 1-212-591-7836 F: 1-212-591-7441
E-mail: engfnd@aol.com
WWW: http://www.engfnd.org
Sunday, August 1, 1999
4:00 p.m. - 6:00 p.m. Registration
6:00 p.m. - 7:30 p.m. Dinner
7:30 p.m. - 7:45 p.m. Opening Remarks
SESSION I: PHOTODYNAMIC
THERAPY: FUNDAMENTAL AND CLINICAL
STUDIES
Session Chair:
Tayyaba Hassan, Wellman Laboratories
8:00 p.m. - 8:30 p.m. An Overview
of Photodynamic Therapy Mechanisms
D. Kessel, Wayne State University School
of Medicine
8:30 p.m. - 9:00 p.m. Photodymanic
Therapy for the Treatment of Age-Related
Macular Degeneration
J. Levy, QLT PhotoTherapeutics, Inc.
9:00 p.m. - 9:30 p.m. Cardiovascular
Applications of Photodynamic Therapy
K. Woodburn, Pharmacyclics
9:30 p.m. - 10:00 p.m. Photodynamic
Therapy with Levulan® and a Primer on the
FDA Approval Process
S.L. Marcus, DUSA Pharmaceuticals, Inc.
10:00 p.m. - 11:00 p.m. Social Hour
Monday, August 2, 1999
7:00 a.m. - 8:30 a.m. Breakfast
SESSION II: FRONTIERS FOR SPECTROSCOPY:
IN VITRO DIAGNOSTIC
Session Chair:
Rebecca Richards-Kortum, University of Texas at Austin
8:30 a.m. - 9:00 a.m. Quantitative
Biomarkers: Risk of Progression and Role in
Cancer Chemoprevention Trials
C.W. Boone, National Institute of Health,
Bethesda
9:00 a.m. - 9:30 a.m. Biological
Basis of Cervical Tissue Fluorescence and
Correlation with Biomarkers
M. Follen Mitchell, MD Anderson Cancer
Center, Houston
9:30 a.m. - 10:00 a.m. Biological
Basis of Bronchial Tissue Autofluorescence and
Correlation with Biomarkers
S. Lam, British Columbia Cancer Agency,
Vancouver
10:00 a.m. - 10:30 a.m. Coffee Break
10:30 a.m. - 11:00 a.m. Multi-Spectral
Reflectance Imaging of the Cervix in Vivo
B. Pogue, Darmouth
11:00 a.m. - 12:00 noon Discussion
12:00 noon - 1:30 p.m. Lunch
1:45 p.m. - 5:45 p.m. Ad hoc sessions and/or free time
5:45 p.m. - 7:15 p.m. Dinner
SESSION III: FRONTIERS IN SPECTROSCOPY:
TISSUES
Session Chair: Michael
Feld, Massachusetts Institute of Technology
7:30 p.m. - 8:00 p.m. Neural
Network Assisted Analysis for Screening Cervical
Smears
L.J. Mango, Neuromedical Systems
8:00 p.m.- 8:30 p.m. NIR Reflectance
Spectroscopy for Glucose Measurement
M. Arnold, University of Iowa
8:30 p.m. - 9:00 p.m. Coffee Break 9:00 p.m. - 9:30 p.m. Relationship Between Spectroscopy and Pathology Mary Ann Fitzmaurice, Case Western Reserve University & University Hospitals, Cleveland
9:30 p.m. - 10:00 p.m. PANEL DISCUSSION
Fluorescence, Reflectance or Raman:
Which is better technique?
Fluorescence!
Tuan Vo Dinh, Oak Ridge National Laboratory
Reflectance!
Irving Bigio, Los Alamos National Laboraory
TBA
D. Bornhop
10:00 p.m. - 11:00 p.m. Social Hour
Tuesday, August 3, 1999
7:00 a.m. - 8:30 a.m. Breakfast
SESSION IV: PHOTON MIGRATION
Session Chair:
Bruce Tromberg, Beckman Laser Institute, University of California
at Irvine
8:30 a.m. - 9:00 a.m. Continuous
Bedside Monitoring and Imaging of Brain
Oxygenation
D.T. Delpy, Department of Medical Physics
& Bioengineering, University College London
9:00 a.m. - 9:30 a.m. Laser Mammography
and Non-Invasive Optical Monitoring of
Cerebral Activity
S. Fantini, Department of Physics, University
of Illinois at Urbana-Champaign
9:30 a.m. - 10:00 a.m. Photon
Migration Imaging and Spectroscopy
M.S. Patterson, Hamilton Cancer Center
10:00 a.m. - 10:30 a.m. Coffee Break
10:30 a.m. - 11:00 a.m. Optical
Mammography
D. Boas, Harvard University
11:00 a.m. - 12:00 noon Panel Discussion
B. Chance, University of Pennsylvania
12:00 noon - 1:30 p.m. Lunch
1:45 p.m. - 5:30 p.m. Ad hoc sessions and/or free time
5:45 p.m. - 7:15 p.m. Dinner
SESSION V: ADVANCES IN TISSUE MICROSCOPY,
DYES AND
REPORTERS
Session Chair: Robert
Webb, Massachusetts General Hospital
7:30 p.m. - 8:00 p.m. The Best
Current in Vivo Microscopy: Live Confocal
Microscopy
M. Rajadhyaksha, Lucid, Inc.
8:00 p.m. - 8:30 p.m. The Best
Current Vital Imaging Via Catherer - OCT: A
Catherer-Delivered Optical Coherence
Tomography Imager
B. Bouma, Wellman Laboratories of Photomedicine
8:30 p.m. - 9:00 p.m. Coffee Break
9:00 p.m. - 9:30 p.m. Luciferase
Reporter Gene
C. Contag, Stanford University
9:30 p.m. - 10:00 p.m. Functional
Genomics: An Introduction
M. Zoller, Ariad Pharmaceutics
10:00 p.m. - 11:00 p.m. Social Hour
Wednesday, August 4, 1999
7:00 a.m. - 8:30 a.m. Breakfast
SESSION VI: ADVANCES IN CELL MICROSCOPY:
SPECTROSCOPY AND
MICROMANIPULATION
Session Chair: Daniel
Farkas, University of Pittsburgh and Carnegie Mellon University
8:30 a.m. - 9:00 a.m. TBA
T. Yanagida, Osaka University
9:00 a.m. - 9:30 a.m. Labelling
DNA for Sensitive Detection
A. Waggoner, Amersham Pharmacia
9:30 a.m. - 10:00 a.m. Coffee Break
10:00 a.m. - 10:30 a.m. TBA
S. Hell, Max Planck Institute for Biophysical
Chemistry
10:30 a.m. - 11:00 a.m. TBA
T. Wilson, University of Oxford
11:00 a.m. - 12:00 noon Discussion
12:00 noon - 1:30 p.m. Lunch
2:30 p.m. - 5:30 p.m. POSTER SESSION
6:00 p.m. - 7:30 p.m. Dinner
SESSION VII: LASER-TISSUE INTERACTIONS:
THERAPEUTIC
INTERVENTIONS
Session Chair:
Steven Jacques, Oregon Laser Center
7:45 p.m. - 8:15 p.m. Laser Thermal
Shaping of Cartilage Implants
B. Wong, Beckman Laser Institute
8:15 p.m. - 8:45 p.m. Laser Thrombolysis:
Clearing Vessel Clots in Heart and
Brain
S. Prahl, Oregon Medical Laser Center
8:45 p.m. - 9:15 p.m. Coffee Break
9:15 p.m. - 9:45 p.m. Photochemically
Activated Adhesives for Tissues
Anastamosis
M. Judy, Baylor Research Institute
9:45 p.m. - 10:15 p.m. Discussion
10:15 p.m. - 11:15 p.m. Social Hour
Thursday, August 5, 1999
7:00 a.m. - 8:30 a.m. Breakfast
SESSION VIII: OPTICS FOR BIOTECHNOLOGY
Session Chair:
Tom Baer, Arcturus
8:30 a.m. - 9:00 a.m. Simultaneous
10 Channel Fluorescence Tagging and Flow
Cyometric Analysis of Leukocytes:
Applications to Immune System Monitoring and HIV
M. Roederer, Stanford University
9:00 a.m. - 9:30 a.m. Gene Expression
Analysis Using Laser Capture
Microdissection and Fluorescent
cDNA Microarrays
M. Erlander, R.W. Johnson Pharmaceutical
Institute
9:30 a.m. - 10:00 a.m. Coffee Break
10:00 a.m. - 10:30 a.m RNA/DNA
Molecular Diagnostics: Applications to Cancer
Diagnosis
S. Bova
10:30 a.m. - 11:00 a.m. TBA
R. Bonner, National Institute of Health
11:00 a.m. - 12:00 noon Discussion
12:00 noon - 1:30 p.m. Lunch
LUNCHEON SPEAKER
D.S. Coffey, Johns Hopkins
Molecular Biology of Cancer:
Vision of the Future
1:45 p.m. - 6:30 p.m. Ad hoc sessions and/or free time
7:00 p.m. - 10:30 p.m. Luau
Friday, August 6, 1999
7:00 a.m. - 8:30 a.m. Breakfast
SESSION IX: BIOMEDICAL OPTICS RESEARCH
FOR THE 21ST CENTURY
Session Chair:
Tom Deutsch, Wellman Laboratories, Massachusetts General Hospital
8:30 a.m. - 9:00 a.m. The Future
of MR, PET and Optical Imaging
R. Lenkinski, University of Pennsylvania
9:00 a.m. - 9:30 a.m. Optics
in Medicine
F. Hillenkamp, Muenster
9:30 a.m. - 10:00 a.m. Coffee Break
10:00 a.m. - 12:30 p.m. Industry
Agency, Roundtable Discussion Including
Preparation of Meeting Summary
by Chairs and Session Organizers
12:30 - 2:00 p.m. Lunch
2:00 p.m. - Conference adjournment