2. High-throughput metabolic flux profiling in batch culture
Eliane Fischer, Uwe Sauer, Institute of Biotechnology,
ETH Zürich, Switzerland
3. Methodological innovations in 13C-labeling based
metabolic network and flux analysis applied to P. Chrysogenum
and S. Cerevisiae
Wouter A. van Winden, Jan C. van Dam, Walter M. van Gulik,
Peter J.T. Verheijen, Joseph J. Heijnen, Kluyver Laboratory for
Biotechnology, Delft University of Technology, The Netherlands
4. Time-lagged statistical analysis for improved metabolic
engineering
Kenneth J. Kauffman, Jeremy S. Edwards, University of Delaware,
USA
5. Uncertainties and measurement errors in 13C metabolic
flux analysis
Wolfgang Wiechert, Aljoscha Wahl, Katharina Nöh, University
of Siegen, Germany
6. Applied system biology; process development in bioreactors
using statistical designs. impact of dissolved CO2
on performance at 2Ll, 400L and 2000L scales
Neslihan DelaCruz, Gordon Crupi, Tina Etcheverry, Genentech,
Inc., USA
7. Elementary mode analysis to analyze flux distributions in
lactobacillus rhamnosus on multiple substrates
David A Fell, M. G. Poolman, Oxford Brookes University,
UK
V. K. Venkatesh, B. D. Jyoti, IIT Bombay, India
8. Metabolic engineering analysis of disease: Hepatic metabolism
Francois Berthiaume, Shriners Hospital for Children, USA
Kyongbum Lee, Gregory N. Stephanopoulos, Massachusetts Institute
of Technology, USA
Scott Banta, Martin L. Yarmush, Massachusetts General Hospital,
USA
9. Application of linlog kinetics in metabolic modeling
J.J. Heijnen, M.T.A.P. Kresnowati, F.O. Aboka, W.M. van
Gulik, Delft University of Technology, The Netherlands
D. Visser, Purac Biochem BV, The Netherlands
10. Transcriptome and proteome analysis of Saccharomyces
cerevisiae metabolic response to glucose and ethanol as carbon
sources
Pascale Daran-Lapujade, Mariela Serrano-Davalos, Marijke
A.H. Luttik, Walter van Gulik, Jack T. Pronk, Technical University
of Delft, The Netherlands
11. Use of a pathway distance metric through linear programming
for the analysis of metabolic networks
Evangelos Simeonidis, Stuart C.G. Rison, I. David L. Bogle,
Lazaros G. Papageorgiou, University College London, UK
Janet M. Thornton, European Bioinformatics Institute, Wellcome
Trust Genome Campus, UK
12. Metabolic flux analysis of adenovirus production in perfusion
cultures of 293 cells
Olivier Henry, Amine Kamen, NRC Biotechnology Research
Institute, Canada
Michel Perrier, Ecole Polytechnique de Montreal, Canada
13. Searching the metabolome: Toward in silico metabolic pathway
engineering
Daniel McShan, Imran Shah, University of Colorado Health
Science Center, USA
14. Reconstruction of the dynamic oxygen uptake rate and carbon dioxide evolution
rate during a pulse experiment
L. Wu, H.J. Bloemen, W.M. van Gulik, M.H.G. Verhaegen,
J.J. Heijnen, Delft University of Technology, Kluyver Laboratory,
The Netherlands
15. ScrumPy - An object oriented software package for metabolic modelling
Mark G. Poolman, David A. Fell, Oxford Brookes University,
UK
16. Minimal perturbation analysis of metabolic gene knockouts
Daniel Segre, Dennis Vitkup, George M. Church, Harvard
Medical School, USA
17. Analysis of global structure and evolution of genome-based
metabolic networks
Jibin Sun, An-Ping Zeng, Hongwu Ma, German Research Center
for Biotechnology, Germany
18. A global optimization approach for metabolic flux analysis
Carlos Arturo Martinez Riascos, Andreas Karoly Gombert,
Jose Mauricio Pinto, University of Sao Paulo, Brazil
19. Effect of culture conditions on growth, productivity, and
proteome of CHO cells expressing recombinant proteins
Soo Young Stanford Lee, Matthias Brand, Keli Ou, Susan
Lee Teck Lian, Biopharmaceutical Manufacturing Technology Centre
(BMTC), Singapore
Jaeseung Yoon, Kyung Hee University, Korea
20. Antithrombotic protection of the vascular wall by modified
antioxidant enzymes
Alexander V. Maksimenko, Vladimir.L.Golubykh, Elena.G.Tischenko,
Russian Cardiology Research Center, Russia
21. Application of metabolic engineering and multivariate analyses
to optimize hepatic function
Christina Chan, Michigan State University, USA
Daehee Hwang, George Stephanopoulos, Gregory Stephanopoulos,
MIT, USA
Martin L. Yarmush, Harvard Medical School/Mass General
Hospital, USA
22. Integrating fluxes, metabolite concentrations and enzyme
activities for the predictive modeling of metabolic regulation
Eric von Lieres, Wolfgang Wiechert, University of Siegen,
Germany
Sören Petersen, Metabolic Explorer GmbH, Germany
23. Metabolic Activity Profiling: Merging dynamic flux analysis
and metabolomics
Sören Petersen, Albert A. de Graaf, Metabolic
Explorer GmbH, Germany
24. Inferring gene regulatory networks from DNA microarray
time series data
Costas D. Maranas, Anshuman Gupta, Pennsylvania
State University, USA
25. C463A, A spontaneous mutant derived from Sp2/0, is capable
of growth in chemically defined media and high IgG expression
ChiChang Lee, Celia Ly, Gill Carton, Xiaomei Shi,
Edward Savino, Tina Lee, Gordon Moore, Fred Bader, Centocor, Johnson
& Johnson, USA
26. Roles of mannitol and glycerol in Aspergillus stress response
George Ruijter, Leiden University Medical Centre, Netherlands
Maarten Bax, Simon Flitter, Ronald de Vries, Utrecht University,
Netherlands
Jaap Visser, FGT Consultancy, Netherlands
27. Osmoregulation of the hexose-phosphate recycling in Sinorhizobium
meliloti
Isabelle Gosselin, Inés Garbayo, Jean-Noël
Barbotin, Laboratoire de Génie Cellulaire, Université
de Picardie-Jules Verne, France
Jean-Charles Portais, Centre de Bioingénierie Gilbert
Durand, France
28. Analysis on kinetic sugar metabolism of suspension plant
cells pre-cultured under various conditions by mid-infrared spectroscopy
Atsushi Hashimoto, Akiko Kurokawa, Kenichi Nakanishi,
Takaharu Kameoka, Mie University, Japan
29. Development of quantification system of ionic dissociative
materials in glycolytic pathway using an FT-IR/ATR method
Tao Pan, Kenichi Nakanishi, Atsushi Hashimoto, Takaharu
Kameoka, Mie University, Japan
30. Metabolic modelling as a tool for the study of the metabolism
of neurotransmitter glutamate in rat cerebral cells
Aristotle Chatziioannou, F.N. Kolisis, National Technical
University of Athens, Greece
G. Palaiologos, University of Athens, Greece
31. Structure and dynamics of the TGF-beta signaling network
Julio Saez-Rodriguez, Andreas Politzer, Knut Behrendt,
Matthias Reuss, Klaus Mauch, Institute of Biochemical Engineering,
Germany
32. Modular visualization and analysis of large-scale cellular
networks
Matthias Reuss, Henning Schladebach, Institute of Biochemical
Engineering, Germany
Knut Behrendt, Michael Dauner, Klaus Mauch, INSILICO Biotechnology
GmbH, Germany
33. A nutritional and metabolic model describing hairy roots
growth and secondary metabolites production
Mario Jolicoeur, Mathieu Leduc, Cyril Tikhomiroff,
Ecole Polytechnique de Montreal, Canada
34. Integration of transcriptome data into genome-scale metabolic
models
Mats Åkesson, Jochen Förster, Christoffer Bro,
Steen Lund Westergaard, Jens Nielsen, BioCentrum-DTU, Denmark
35. Genetic strategies directed to protect hybridoma cultures
from apoptosis
Joaquim Vives, Sandra Juanola, Jordi J. Cairó,
Francesc Godia, Dep. d'Enginyeria Química, ETSE, UAB, Spain
Eva Prats, L. Cornudella, Dep. de Biologia Molecular i Cellular,
IBMB, CSIC, Spain
36. Quantification of metabolic fluxes in developing soybean
(Glycine max) embryos
Ganesh Sriram, D. Bruce Fulton, Mark E. Westgate, Martin
H. Spalding, Jacqueline V. Shanks, Iowa State University, USA
37. Combining NMR study and genomic analysis to understand
glucose metabolism of Propionibacterium freudenreichii
subsp. shermanii
Catherine Deborde, Guillaume Meurice, Daniel Jacob, Diliana
Dimova, INRA-Laboratoire de Recherche de Technologie Laitière,
France
Patrick Boyaval, Rhodia Food Dangé Laboratories, France
38. Metabolic fluxes in riboflavin-producing bacillus subtilis
during transient states
Nicola Zamboni, Eliane Fischer, Uwe Sauer, ETH Zürich,
Switzerland
Hans-Peter Hohmann, Roche Vitamins Inc., Switzerland
39. Proteomic analysis of metabolic changes in fed-batch CHO
cell cultures
Deborah E. Pascoe, David Arnott, Dana C. Andersen, Genentech,
Inc., USA
William M. Miller, E. Terry Papoutsakis, Northwestern
University, USA
40. MEtabolic TRer ANalysis (METRAN): Software for metabolic
flux analysis and isotopomer spectral analysis
Maciek R. Antoniewicz, Gregory Stephanopoulos, Massachsetts
Institute of Technology, USA
Joanne K. Kelleher, George Washington University, USA
41. Using mathematical modelling for reconstruction of regulatory
pathways
Mikkel Nordkvist, Morten Skov Hansen, Jens Nielsen, John
Villadsen, Center for Process Biotechnology, Technical University
of Denmark, Denmark
42. Investigation of network topology and quantification of
fluxes in central carbon metabolism of Aspergilli under
different conditions of glucose repression
Helga David, Mats Åkesson, Jens Nielsen, BioCentrum-DTU,
Technical University of Denmark, Denmark
43. Eukaryotic metabolism investigated through yeast model
by multiple substrate feeding strategy and labelling experiments
Kashif Sheikh, Lars K. Nielsen, University of Queensland,
Australia
44. Characterization of differential protein expression associated
with adaptation of NSO transfected cell line to protein-free medium
Kathya R. de La Luz Hernández, Yamilet Rabasa,
Svieta Victores, Adolfo Castillo Vitlloch, Lila Castellanos, Center
of Molecular Immunology, Cuba
45. Study of apoptosis induction mechanisms in NSO recombinant
myeloma cell line as selection criteria for inverse cell engineering
Adolfo Castillo Vitlloch, Svieta Víctores,
Evelyn Faife, Kathya R. de la Luz Hernández, Center of
Molecular Immunology, Cuba
46. Pathway reconstruction in Saccharomyces cerevisiae:
Using DNA array data from deletion mutants
Steen Lund Westergaard, Christoffer Bro, Steen Knudsen,
Lisbeth Olsson, Technical University of Denmark, Denmark
47. Brown-adipocyte differentiation: A metabolic-engineering
challenge to quantify the roles of genes, hormones, metabolites,
and signaling cascades
Hyuntae Yoo, Joanne K. Kelleher, Gregory Stephanopoulos,
Massachusetts Institute of Technology, USA
48. Modeling and analysis of large-scale translation networks
Vassily Hatzimanikatis, Amit Mehra, Northwestern University,
USA
49. Metabolic engineering of Escherichia coli for the
production of polyhydroxyalkanoates consisting of short-chain-length
and medium-chain-length monomers
Jong Hyun Choi, Jong Pil Park, Si Jae Park, Sang
Yup Lee, Korea Advanced Institute of Science and Technology, Korea
50. Expression of pyruvate carboyxlase improves recombinant
protein production in Escherichia coli
Mark A. Eiteman, Elliot Altman, John C. March, University
of Georgia, USA
51. Design of precursor supply from central carbon metabolism
in a wildtype strain and in an overproducer
J. W. Schmid, K. Mauch, M. Reuss, Institute of Biochemical
Engineering, Germany
A. Kremling, Max-Planck-Institut für Dynamik komplexer technischer
Systeme, Germany
52. Reducing the complexity of kinetic models of metabolic
networks
Ziomara P. Gerdtzen, Prodromos Daoutidis, Wei-Shou Hu,
University of Minnesota, USA
53. Metabolic engineering of Escherichia coli for the
production of medium-chain-length polyhydroxyalkanoates
Seung Hwan Lee, Si Jae Park, Jong Pil Park, Sang Yup Lee,
Korea Advanced Institute of Science and Technology, Korea
54. Elucidation of the metabolic fate of glucose in Trichoderma
reesei using EST analysis and cDNA microarray: A step toward
metabolic engineering of the regulatory networks for anaerobic
metabolism of glucose
Hamza El-Dorry, Felipe Chambergo, Ynés Valencia
Morante, University of São Paulo, Brazil
55. Comparative network analysis of a strain genealogy of lysine
producing corynebacteria - tracing back the history of strain
optimization for future targeted design
Elmar Heinzle, Christoph Wittmann, Biochemical Engineering,
Saarland University, Germany
56. Metabolic engineering of cell cycle and apoptosis genes
Mohamed Al-Rubeai, Shikiko Watanabe, Neysi Ibarra, Jingxiu
Bi, John Shuttleworth, University of Birmingham, UK
57. Integration of metabolic flux distributions with gene and
protein expressions
Kazuyuki Shimizu, Yang Chen, Kyushu Institute of Technology,
Japan
Hua Qiang, Jiao Zhao, Keio University, Japan
58. Steady state simulation of signal transduction systems
K. V. Venkatesh, Vivek Mutalik, Indian Institute of Technology,
India
Aditya P Singh, Jeremy Edwards, University of Delaware,
USA
59. A phenotype phase plane analysis of the synthesis of recombinant
SOD in yeast
B.A. Andrews, J.A. Asenjo, C. Basulto, University of Chile,
Chile
R. Gonzalez, Iowa State University, USA
60. Metabolic engineering of Catharanthus roseus hairy roots
using an inducible promoter
Ka-Yiu San, Erik Hughes, Seung-Beom Hong, Sue Gibson,
Rice University, USA
Jacqueline V. Shanks, Iowa State University, USA
61. Validation of a predictive Escherichia coli metabolic
model
Jason R. DiTonno, Jeremy Edwards, University of Delaware,
USA
62. Volatile anesthetic Halothane causes cell damage
Tanya Topouzova, Vesselina Moskova, Elena Stephanova,
Sofia University, Bulgaria
Paula Daza, Seville University, Spain
63. Quantitative and qualitative analysis of phospholipids
released in the culture medium from A549 human lung carcinoma
cell line
Ralitza Valtcheva, Albena Jordanova, Elena Stephanova,
Zdravko Lalchev, Sofia University, Bulgaria
64. Cofactor engineering of Acetyl-CoA and its subsequent effect
on metabolic flux redistribution and the production of ester in
E. coli
Ka-Yiu San, George N. Bennett, Ravi V. Vadali, Rice University,
USA
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