2. Experimental and modeling approaches to the metabolic engineering of methylobacterium extorquens AM1
Stephen J. Van Dien, Mary E. Lidstrom, University of Washington, USA

3. Comparative study of regulation of glutamate production in corynebacterium glutamicum and corynebacterium efficiens'
Hiroshi Shimizu, Akinori Nakato, Keisuke Nagahisa, Suteaki Shioya, Osaka University, Japan

4. Pressure modifications: Piezotolerance as a metabolic engineering tool for the biosynthesis of natural products
Phillip C Wright, Robin E Westacott, Adam M Burja, Heriot-Watt University, UK

5. Identifying functionally important protein regions via protein family correlation analysis and atomistic energy calculations
Costas D. Maranas, Gregory L. Moore, Manish C. Saraf, The Pennsylvania State University, USA

6. A new route for chlorosalicylate degradation by an interplay of enzymes from separate pathways
Patricia Nikodem, Dietmar H. Pieper, German Research Center for Biotechnology, Germany

7. Higher-throughput metabolic flux analysis of mammalian cells
Robert Balcarcel, Lindsey M. Clark, Sean M. Hartig, Yuansheng Yang, Vanderbilt University, USA

8. Metabolic engineering of the cysteine biosynthetic pathway: A means for the production of natural and unnatural amino acids
Thomas H.P. Maier, Wacker-Chemie GmbH (Consortium), Germany

9. Towards high throughput metabolic activity profiling using MALDI-TOF mass spectrometry and microtiterplate reactors
Elmar Heinzle, Christoph Wittmann, Saarland University, Germany

10. Sensor reactor - a novel tool for serial mapping of microbial carbon flux distributions in production processes
R. Takors, M. El Massaoudi, A. Drysch, H. Sahm, A. A. de Graaf, Institute of Biotechnology, Forschungszentrum Jülich GmbH, Germany

11. From at-line to in-situ bioprocess monitoring using near infrared spectroscopy
S. Alison Arnold, Linda M. Harvey, Brian McNeil, Strathclyde Fermentation Centre, University of Strathclyde, UK

12. Model based design of expression systems for the production of recombinant proteins in process development
Martin Siemann-Herzberg, Sabine Arnold, Matthias Reuss, Institute of Biochemical Engineering, University Stuttgart, Germany

13. The bacillus operating system
Gopal Chotani, Karl Sanford, Eugenio Ferrari, Fernando Valle, Anita Van Kimmenade, Genencor International, USA

14. Unravelling the full metabolome of bacillus subtilis
Mariët J. van der Werf, TNO Food, The Netherlands

15. Lutein biosynthesis in stenotrophomonas bacterial cultures: channeling of carotenoids to lutein biosynthesis by light irradiation and its cytotoxic effects
S. Ramachandra Rao, S. Yamamura, Y. Morita, E. Tamiya, Japan Advanced Institute of Science and Technology, Japan

16. Integrated use of genomic and proteomic data and enzyme activity assay for metabolic pathway analysis and optimization of microbial production of 1,3-propanediol
J. Sun, A.-P. Zeng, W. Wang, M. Hartlep, W.-D. Deckwer, GBF - German Research Centre for Biotechnology, Germany

17. Metabolic engineering of escherichia coli for the production of IGF-1 by transcriptome analysis
Jong Hyun Choi, Seok Jae Lee, Sang Yup Lee, KAIST, Korea

18. Activity and stability of chromobacterium viscosum lipase in modified AOT reverse micelles
M.M.R. Talukder, Y. Hayashi, T. Takeyama, Y. Yanai, T. Kawanishi, Kanazawa University, Japan

19. Lipase catalyzed synthesis of biodiesel by the esterification of fatty acids and short chain alcohol
Tan Tianwei, Deng Li, Wang Fang, Beijing University of Chemical Technology, China

20. Metabolic engineering of a novel propionate-independent biosynthetic pathway for propionyl-CoA
Jay D. Keasling, Ilana S. Aldor, Seon-Won Kim, Kristala L. Jones Prather, University of California, Berkeley, USA

21. Metabolic engineering of lactic acid bacteria for enzyme production
Amit Vasavada, Roxanna Halich, Gordana Djordjevic, Diversa Corporation, USA

22. High-throughput method for generating transposon-tagged mutations in the genome of escherichia coli using in vitro transposition: Rapid identification of essential genes
Vasantha Nagarajan, Kyle Knoke, Sean Huang, Pamela Sharpe, DuPont, USA

23. Production of an unnatural amino acid by manipulating natural metabolic pathways
Shin-ichi Hashimoto, Technical Research Laboratories, Kyowa Hakko Kogyo Co., Ltd., Japan
Ryoichi Katsumata, Laboratory of Animal Microbiology, Tohoku University, Japan

24. Genetic engineering of escherichia coli for production of tetrahydrobiopterin
Katsuhiko Yamamoto, Eri Kataoka, Nobue Miyamoto, Kazuhiro Ohsuye, Masayuki Yabuta, Suntory Institute for Medicinal Research and Development, Japan

25. Resolution of multiple formaldehyde assimilatory networks encoded in the genome of the obligate methanotroph, methylomonas sp. 16a
E.S. Miller Jr, B.D. Tyreus, M. Koffas, P.L. Sharpe, J. M. Odom, DuPont Central Research and Development, USA

26. Engineering saccharomyces cerevisiae for improving synthesis of chiral alcohols
Mikael Katz, Bärbel Hahn-Hägerdal, Marie-Francoise Gorwa-Grauslund, Lund University, Sweden

27. Metabolic engineering of an obligate methanotroph for the production of carotenoids
Stephen Picataggio, John Seip, Deana Dicosimo, Edward S. Miller, Jr., Martin Odom, DuPont Central Research and Development, USA

28. Metabolomics: Applications in microbiology
Nicole van Luijk, Mariët J. van der Werf, TNO Food, Netherlands

29. Approaches for enhancing xylose uptake by the xylose-utilising S. cerevisiae
Anu Saloheimo, John Londesborough, Merja Penttilä, Laura Ruohonen Cell Factory, VTT Biotechnology, The Netherlands
Michael C. Walsh, Heineken Technical Services, The Netherlands

30. Engineering of saccharomyces cerevisiae for the production of L-glycerol 3-phosphate
Elke Nevoigt, Huyen Thi Thanh Nguyen, Ulf Stahl, Technische Universität Berlin, Germany
Karin Athenstaedt, Technische Universität Graz, Austria
Truong Nam Hai, Vietnam National Centre for Natural Science and Technology, Vietnam

31. Distribution of metabolic fluxes in mutant strains of Streptomyces coelicolor with impaired pentose-phosphate pathway activity
Claudio Avignone-Rossa, S. Sequeira, M. Bushell, School of Biomedical & Life Sciences - UniS, University of Surrey, UK
M. Butler, K. Chater, Dept of Molecular Microbiology, John Innes Centre, UK

32. Target identification and metabolic engineering driven by genome-wide transcription profiling
J. Bauer, J. Brill, S. Bettermann, S. Weich, O. Sorgenfrei, Axaron Bioscience AG, Germany

33. Gene disruption in Klebsiella pneumoniae for metabolic engineering of 1,3-propanediol
Ping Zheng, Jibin Sun, Joop van den Heuvel, An-Ping Zeng, GBF- German Research Center for Biotechnology, Germany

34. Heterologous expression of the Escherichia coli genes pgm, galu, otsa and otsb in Corynebacterium glutamicum, and their impact on trehalose biosynthesis
Leandro Padilla, Eduardo Agosin, Pontificia Universidad Católica de Chile, Chile
Gregory Stephanopoulos, Massachusetts Institute of Technology, USA
Reinhard Krämer, Universität zu Köln, Germany

35. Metabolite flux balancing to increase lysine yield from C-substrates by Brevibacterium flavum RC 115
Ruklisha Maija, Paegle Longina, Denina Ilze, University of Latvia, Latvia

36. A functional protein chip for in vitro metabolic engineering
Gyoo Yeol Jung, Gregory Stephanopoulos, Massachusetts Institute of Technology, USA

37. Optimization of ethanol production process through metabolic flux modelling
Guillouet S.E., Alfenore S., Goma G., Bideaux C., Uribelarrea J.L., Laboratoire de Biotechnologies et Bioprocedes, INSA-DGBA, France

38. A novel fermentative process for the preparation of D-pantothenate
Dr. Christine Beck, Dr. Hans-Peter Harz, Dr. Daniela Klein, Dr. Markus Lohscheidt, Dr. Edzard Scholten, BASF AG, Germany
Dr. Theron E. Hermann, Dr. Thomas A. Patterson, Dr. Janice G. Pero, Dr. R. Rogers Yocum, OmniGene Bioproducts Inc., USA

39. Increased microbial production of alpha-lipoic acid and biotin by overexpression of iron-sulfur cluster genes
Hans Liao, Sara McFarlan, Cargill, Inc., USA

40. Metabolic engineering for the production of 3-hydroxypropionic acid by fermentation
Ravi Gokarn, Cargill, Inc., USA

41. Cloning and sequence analysis of genes encoding enzymes for trehalose biosynthesis from thermophilic archaebacterium Sulfolobus shibatae B12
Jin Wu, Wei-ting Yu, Shao-xiao Wang, Ke-qian Yang, Shu-zheng Zhang, Chinese Academy of Sciences, China

42. Anti-sense rna: A metabolic engineering tool, used to regulate overflow metabolism in Escherichia coli
Helen Irvine, John Ward, Yuhong Zhou, Frank Baganz, University College London, UK

43. Isolation and characterisation of the putative alpha and beta subunits of propionyl-CoA carboxylase from Sinorhizobium meliloti
Jean-Charles Portais, Centre de Bioingénierie Gilbert Durand, France
Renaud Bouat, Isabelle Prost, Brigitte Thomasset, Université de Technologie de Compiègne, France

44. A metabolic engineering approach to examine the interaction between primary and secondary metabolism for the production of polyketides by Saccharopolyspora erythraea
Misti Ushio, John M. Ward, Frank Baganz, University College London, UK
Matthew A. Gregory, Peter F. Leadlay, University of Cambridge, UK

45. Flux balance analysis of Saccharopolyspora erythraea incorporating changing biomass composition
Colin Jaques, Frank Baganz, John Ward, Yuhong Zhou, University College London, UK

46. The Hyaluronic Acid Synthesis (HAS) operon of streptococci as determinant for high hyaluronic acid production
Lars M. Blank, Lars K. Nielsen, The University of Queensland, Australia

47. Prolonged glucose limited chemostat cultivation affects the metabolic response of S. cerevisiae to a glucose pulse
L. Wu, M.R. Mashego, J.L. Vinke, W.M. van Gulik, J.J. Heijnen, Delft University of Technology, The Netherlands

48. Genomic analysis of osmoregulation in Propionibacterium freudenreichii subsp. shermanii : The glycine betaine case.
Guillaume Meurice, Diliana Dimova, Catherine Deborde, Daniel Jacob, Patrick Boyaval, Institut National de la Recherche Agronomique - Laboratoire de Recherche de Technologie Laitière, France

49. An integrated functional genomics approach towards the improvement of phenylalanine production
Karin M. Overkamp, Mariet J. van der Werf, TNO Nutrition and Food Research, The Netherlands

50. The effect of cytosolic malic enzyme on anaerobic xylose fermentations
Eija Rintala, Laura Ruohonen, John Londesborough, Jaana Uusitalo, Merja Penttilä, VTT Biotechnology, Finland

51. The first fungal NADP-dependent GAPDH from Kluyveromyces lactis
Ritva Verho, Peter Richard, John Londesborough, Merja Penttilä, VTT Biotechnology, Finland

52. Proteome and transcriptional analysis of recombinant xylose utilising Saccharomyces cerevisiae
Laura Salusjärvi, Laura Ruohonen, Merja Penttilä, VTT Biotechnology, Finland
Marjo Poutanen, Nisse Kalkkinen, University of Helsinki, Finland

53. Expression of the yeast mevalonate-dependent isoprenoid biochemical pathway for the production of sesquiterpenes in Escherichia coli
Vincent J.J. Martin, Doug Pitera, Sydnor Withers, Jack D. Newman, Jay D. Keasling, University of California-Berkeley, USA

54. Long-term aerobic glucose-limited chemostat cultivation of Saccharomyces cerevisiae CEN.PK 113-7D
M R Mashego, MLA Jansen, W M Van Gulik, JL Pronk, J J Heijnen, Kluyver Laboratory for Biotechnology, Technical University of Delft, The Netherlands

55. Xylose metabolism in Saccharomyces cerevisiae by endogenous aldose reductase and xylitol dehydrogenase
Mervi H. Toivari, Laura Salusjärvi, Laura Ruohonen, Merja Penttilä, VTT Biotechnology, Finland

56. New derivatization method for analysis of intracellular metabolites from central metabolism using GC-MS
Silas Granato Villas-Boas, Margarida Moreira dos Santos, Mats Åkesson, Jens Nielsen, Technical University of Denmark, Denmark

57. Enhanced xylose utilization by the Saccharomyces cerevisiae strain TMB 3400; pieces of the puzzle
Garth Cronwright, Marie Francoise Gorwa-Grauslund, Gunar Liden, Bärbel Hahn-Hägerdahl, Lund Institute of Technology, Lund University, Sweden

58. Resolution of racemic compounds by genetically immobilized lipase
Seung Hwan Lee, Jong Hyun Choi, Sang Yup Lee, Korea Advanced Institute of Science and Technology, Korea

59. DNA-array and western analysis of GroESL over-expression to enhance solvent tolerance in Clostridium acetobutylicum
Christopher Tomas, Eleftherios T. Papoutsakis, Northwestern University, USA

60. Engineering Deinococcus radiodurans phosphate metabolism for metal precipitation in radioactive waste
Alexandra Holland, University of Washington, USA

61. Metabolic engineering with no parameters
Vassily Hatzimanikatis, Inanc Birol, Northwestern University, USA

62. Modulating the redox metabolism of Saccharomyces cerevisiae
Margarida Moreira dos Santos, Lisbeth Olsson, Jens Nielsen, Technical University of Denmark, Denmark
Peter Kötter, J. W. Goethe University, Germany

63. The Entner-Doudoroff pathway in a glycopeptide producing actinomycete bacterium
Nina Gunnarsson, Jens Nielsen, Technical University of Denmark, Denmark

64. Elucidation of the Corynebacterium glutamicum physiology using stable isotopes and mass isotopomer measurements of biomass hydrolysates
Maria I. Klapa, J.C. Aon, Gregory Stephanopoulos, Massachusetts Institute of Technology, USA

65. Dual-phase fermentation of Escherichia coli for the production of succinic acid
Mark A. Eiteman, Elliot Altman, Goutham N. Vemuri, University of Georgia, USA

66. Mechanisms for import of acetyl-CoA into the mitochondrial matrix of Saccharomyces cerevisiae
Marijke A.H. Luttik, Pascale Daran-Lapujade, Jack T. Pronk, Technical University of Delft, Kluyver Laboratory of Biotechnology, The Netherlands
Hentie A. Swiegers, University of Stellenbosch, South Africa
Peter Kötter, J.W. Goethe Universität Frankfurt, Germany

67. Pyruvate production from glucose by acetate-auxotrophic Escherichia coli
Bott, Michael, Tanja Gerharz, Institute for Biotechnology 1, Research Center Juelich, Germany

68. ¹³C-NMR flux ratio analysis of Saccharomyces cerevisiae growing on glucose or xylose in chemostat cultivations
Hannu Maaheimo, Juha-Pekka Pitkänen, Aristos Aristidou, Merja Penttilä, VTT Biotechnology, Finland
Thomas Szyperski, University of New York at Buffalo, USA

69. Identification and preparation of a neoamylase from Bacillus stearothermophilus
Zhang Ying-jiu, Jilin University, P.R.China

70. Directed evolution of glucoamylase to improve thermostability and substrate specificity
Clark Ford, Yue Wang, Erica Fuchs, Allison McDaniel, Peter J Reilly, Iowa State University, USA

71. Effect of increased NADH availability and pathway manipulations on succinate production in Escherichia coli
Ka-Yiu San, George N. Bennett, Ailen Sanchez, Henry Lin, Rice University, USA

72. Metabolic engineering of Clostridium tyrobutyricum for enhanced butyric acid production from glucose and xylose
Ying Zhu, Shang-Tian Yang, The Ohio State University, USA

73. Physiological role of Carnitine Acetyl Transferase in Crabtree effect in Saccharomyces cerevisiae
Mouret J.R., Goma G., Guillouet S.E., INSA Toulouse, France

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